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Out Toller is 15 months and is due for a round of vaccinations next month. The breeder says they are prone to auto-immune disease and should get the absolute minimum of shots.
So far she has had Parvo, distemper, bordatella and lyme; but not parainfluenza or hepatitis. The breeder again wants us to skip those and has offered to give us the vaccine.

The vet will do whatever we want, but thinks it is negligent not to give DHPP. She says that Tollers are only slightly more likely to get autoimmune disease, but the big thing is that there is no connection between vaccines and autoimmune. H and P are uncommon because most dogs are vaccinated, but they are serious illnesses that can be prevented.

Initially the breeder said excessive vaccinations were bad because her immune system was not mature at 2 months, but presumably it is now.

Just for the record... our first Toller died at 7 of Addisons, but the second made it to 17.

Any advice would be appreciated.
 

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imo DHPP (or at least Distemper and Parvo, if you can get them separately) are non-negotiable unless you know your dog has a serious, life-threatening reaction to the vaccine. Parvo in particular is a horrible thing to go through, and even with the very best care available, it's still highly deadly compared to other communicable diseases. These diseases being uncommon is a result of something called herd immunity, and the issue is that if more and more people stop vaccinating, herd immunity breaks down and those "uncommon" diseases start popping up more and more. Not to get political, but this is why we're seeing outbreaks of human diseases we'd almost eradicated - like measles - in the US. Herd immunity is important for protecting animals that cannot get vaccinated because they do have severe, deadly reactions, as well as for young puppies who haven't completed their vaccination series yet, so I feel it's very important to preserve this for your own dog(s), present and future, and for the canine community as a whole.

You can titer to double-check whether your dog has the antibodies to these diseases, and decide whether to vaccinate based on that, but if the levels come back too low to guarantee protection, definitely vaccinate. Usually after the 1-year booster, Distemper and Parvo can be revisited every 3+ years, with titer testing and/or boosters.

For the rest, so much depends on your lifestyle and the risks in your area. We don't do bordatella, for example, because the only other dogs Sam has close contact with regularly are my in-laws' dogs, and bordatella is more of a problem in high-density situations (boarding kennels, daycare, dog parks, etc.). We have done it in the past when we were making more use of such facilities. Lyme and the others will likewise depend on the prevalence of disease in your area and whether you have a lifestyle that makes your dog more or less at risk - basically, it's your call based on what your vet tells you they feel is high-risk.
 
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