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Two years ago before my son passed away we drove to Utah to see my husband, he was working there and couldnt get the time off for my sons birthday or Easter, I live in Michigan so Utah is pretty far, I took Gypsy to the vet she was all up to date on her shots and I do have an SUV so her crate fit in the back. The vet gave her doggy Xanax just in case she became upset.. She actually did very well, the only issue we did have was when we stopped at a hotel, being a rottweiler she is always on guard so she would BARK at night when we(and other people) would try and sleep... She drank plenty of fluids and ate but she rarely went to the bathroom during our stops.

After my son passed we went back to Utah and this time we didnt do Xanax but Benadryl and again she did fine.. I guess it all depends on the dog, my mom travels to Florida with her maltese and he just chills out in the back seat


good luck!
 
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