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Your dog sounds like she is having an allergic reaction to either the urine or the cleaner you're using. Another thought is that she's possibly allergic to her kibble. Most dogs want to keep their area clean unless they have no choice. What type of environment did you get her from? If she's been forced to lay in her own mess, then she has gotten used to it, and it will be very difficult to housetrain her, I'm afraid, but not impossible. What sized pen do you have her in? For housetraining, a puppy should be in a crate only big enough to turn around in and lay down in. Messes must be immediately cleaned up, so the dog doesn't see it as being "normal".

Puppies need to go outside often - at least once an hour, and also after waking up, after eating, after playing, etc. Take her outside on leash, so she can't get distracted playing. Once she's gone potty, then you can let her off the leash (assuming you have a fenced in yard) to play for a few minutes.

Can you hire a dog walker to let her out during the day, or can you go home at lunch time and let her out? She's learned to pee in her pen, b/c she doesn't have a choice. She's too young to hold it all day. If her "pen" is a crate, you need to clean it with an enzyme cleaner, such as Nature's Miracle (found at any pet store). Otherwise, the scent of the urine will be detected by your pup and will encourage her to go in that spot again. Even if you can't smell the pee after cleaning, she can, unless you clean it thoroughly with an enzyme cleaner.
 
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