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It may be tartar build up or a cavity. I use petzlife oral spray for my dog to maintain his teeth but lots of reviewers said that it removes tartar build up very well. Others on this site gives their dogs raw bones which does the same thing. If that doesn't work, see a vet.
 

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If it is a cavity, you'll need to take her to the vet to take care of it. If it gets really bad, it will have to be removed.
 
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