If you transition slowly I don't think it should cause any upsets. That said, any dog can disagree with any food, so you'll just have to try and see. It's high quality though, so I do recommend it. My firsthand experience is that my dog did fine on it, but didn't love the taste. But she's a bit finicky. When I tried it it was one of the grain-inclusive formulas though, she probably would have enjoyed the Wilderness line more.