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From my experience - not necessarily? Our Newfie, Annabel, was the largest pup in her litter, but she's now the smallest adult. The difference between her and her next largest sibling is about... maybe 5 or 10 pounds, so it's not a HUGE difference. That said, this is only my experience and it might be an anomaly! It also could be down to some people overfeeding, which tends to happen often and is sooooo bad in giant breed dogs (we keep her nice and trim), or the fact that she's female and some of her siblings are male and would typically be larger than her anyway. Lots of different factors.
