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Thank you for the warning, however, I have used Zodiac products in the past without issue, it just might be that your dog is sensitive to the ingredients and/or you got a bad batch. Definitely call your vet and also you may want to call the company as well..
 

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I currently own a Lab mix who has allergies to what seems to be EVERYTHING INCLUDING himself, I have also owned a Chi mix that was the same way. I currently use a spray comprised of one or two of the following essential oils and witch hazel. Citronella, Neem, Lavender, Lemon grass, Peppermint or Cinnamon. I also add AppleCiderVinegar to their water daily and occasionally small amounts of garlic to their food.
 

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I believe the effectiveness of the product(s) wears off in a month. Maybe a call to the vet or someone else on here knows for sure about the bloodstream question?
Yes, depending on the product and the severity of infestation the effectiveness lasts anywhere from 1-3 months.
 
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