I recently heard about a product called "ProDen Plaque off" it's an all natural product made from seaweed. A friend of mine recommended it to me after using it on her Yorkie that had HORRID plaque on her teeth. My oldest boy had some plaque issues on his very back teeth, all the rest of his teeth are absolutely great but no matter what I tried nothing seemed to get that off so I decided to give this stuff a tryyyyy. I started using this product about three weeks ago and already see an improvement in his teeth. It might be worth a shot for you...I was willing to try anything before having to put mine under for a dental cleaning and was skeptical about this stuff but it really seems to work.