Good question, it all depends. My son's dog has incurred over $10,000 in vet bills in 6 months for treatment of Immune Mediated Hemolytic Anemia, and I don't know how much more his treatment will cost in the future. His maintenance meds are $200 month, his periodic transfusions are around $1000, however he is not in any pain, and his quality of life is good with treatment. They spent Christmas week with me, and I can't see stopping treatment as long as there is a chance he can recover. If he was in pain, or not enjoying life, it would be different. I had insurance on him, thank God, but that has been exhausted months ago, and now we pay as we go.