Tether them to you when out of the crate. Take them out every hour at first, and after eating, playing and when they wake up. Clean up accidents with an enzyme cleaner. They sound like they have never been housetrained, so they shouldn't be left unsupervised where you can't interrupt them, or catch them when they look like they are looking for a spot.
I'd get them vet checked for a UTI, especially if you have been withholding water.
I'd get them vet checked for a UTI, especially if you have been withholding water.