I've fed prey model, half raw half kibble, and storebought raw at various points throughout our dog's life. Never had an issue, even when he was a growing pup - but you have to do the research. I stopped doing purely prey model at one point because I couldn't source organs - where most of the vitamins in the diet come from - which isn't safe or healthy as a complete diet. We do mostly storebought raw grinds and kibble these days, because commercial raw diets are quite popular and affordable here, but I still love to get my hands on meaty edible bones regularly. Nothing really substitutes for a good, hard, long chew at an edible bone that makes the dog think and really use those teeth! Ribs are great, if you can get them. Weight-bearing bones need caution because an aggressive chewer can and will break teeth on them.
You have to practice safe meat handling practices. Feed the dog somewhere easily washed, like a bare crate, a towel, etc. or outdoors and handle their food like you would any meat you'd cook for yourself. And there is some infectious risk for the dog and human - salmonella and the like. My household has no small children nor immunocompromised people, so my feeling is that keeping things clean and using common sense (no face kisses after dinner, etc.) makes those risks acceptable. I mean, salmonella pops up in kibble, too. Can't claim it's 100% safe, but nothing really is. And some dogs just plain don't do well on raw. It happens. Some dogs don't do well on top of the line kibble, either, and some dog thrive on the cheapest of grocery store brands. Prey model is all animal products - meat, bone, organ. Sometime green tripe is given (the uncleaned intestinal contents of ruminants like cows), but very little to no plant matter overall. Other people include various levels of veg and/or fruit (most of this does have to be cooked and/or blended for dogs to digest it well). It really depends on what works for you and your dog.
But yeah. The biggest danger to the average dog with a homemade raw diet is imbalances, so absolutely do your research or stick to a commercial raw food that labels itself as a complete diet.