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I agree - significant behavior change is always grounds for a thorough vet exam, especially in an older dog, because it can indicate that there's pain, cognitive decline (Canine Cognitive Dysfunction is a condition that occurs in older dogs and is similar to human dementia), or a health condition like thyroid problems that can cause serious behavior and mood changes.
 
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Sometimes a second opinion is necessary, just like with human medicine. If you can find a group on FaceBook or on an app like NextDoor that's specific for your area (even if it's the whole state) it can be worth asking for vet recommendations there.

What tests did your vet run? Finding something like thyroid problems or Cushings disease requires some in-depth bloodwork that's often sent out to be processed at a specialized lab. CCD - Canine Cognitive Dysfunction - isn't something that shows up one lab tests, but a good vet should be able to discuss her behavior patterns with you and evaluate whether it's likely she's having cognitive issues from that.
 
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