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My puppy is now 13 weeks old and is the typical, rambunctious, aggressively playful with nipping that we work on. He is a high energy breed. However, this the second time taking Credelio and he was extra excitable and anxious both times. The side effects do say it can cause neurological problems but it is associated with seizures and paralyzing symptoms. Not what he exhibits. He has urinated more and has had more accidents both days he took it. Has anyone experienced this?
 

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I've not had any experience with this medication (actually had to consult the Google), but you should talk to your vet about what what you've observed, and possibly have it reported to the company. If I remember correctly, he has a of of herding breed in him? Are you sure that the Embark test came back as clear for the MDR1 gene mutation? It might be worthwhile to have another lab run just the MDR1 test. GenSol, VetGen, and Vetnostics all do the test as a stand-alone.
 

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I've not had any experience with this medication (actually had to consult the Google), but you should talk to your vet about what what you've observed, and possibly have it reported to the company. If I remember correctly, he has a of of herding breed in him? Are you sure that the Embark test came back as clear for the MDR1 gene mutation? It might be worthwhile to have another lab run just the MDR1 test. GenSol, VetGen, and Vetnostics all do the test as a stand-alone.
Good to know, he definitely came back negative for MDR1 gene. Yes herding breeds. He is ok on other meds though.
 

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I would still be extremely careful with any medications with him. Discussing options for flea and tick control with your vet would be a good idea. Also, using medications that aren't broad spectrum would probably be a good idea, like using one medication that is just for heartworm/intestinal parasite protection, and then using a flea/tick treatment only when needed.That's my preferred choice anyway.
 

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I would not give anything that produced noticeable symptoms like excitability and anxiety to a dog and wouldn't give any of the fix-it-all-with-a-pill flea stuff to any puppy. If there's a reaction, it's going to get worse every time, and there are other ways to control fleas.
 
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