I used Adequan for Sor as a preventative. He never showed signs of serious arthritis and only really moved different when the bone cancer got bad. But I do remember him being more spry after the Adequan injection. I would not hesitate to use it again. I also did the IM injections myself (there are some sources that say SQ would work but I've always stuck with IM). However, it's important to know where to do it because if done incorrectly you can hit a nerve with the needle.