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Discussion Starter #1 (Edited)
Some of you may have seen my thread about my senior dog with arthritis. She was originally put on Deramaxx for a two week period to see how it worked for her, and I started her on Dasuquin at the same time.

After coming off of the Deramaxx Gracie's soundness declined again. I would say on Dasuquin alone she is maybe 20% improved from when we originally started management (prior to dasuquin or deramaxx). On the Dasuquin and Deramaxx combined, she was about 50% improved. Had a long chat with the vet weighing options, and we have decided to try Adequan, as well as having Deramaxx on hand to administer if she is having a bad day or if I am planning on a longer walk/hike. I also like that Adequan has much fewer potential side effects than Dasuquin and should be easier on her system (no monitoring of her liver required, aside from her normal yearly blood panel).

Without some sort of pain management employed, I do not walk her at all, nor do I let her stay in the yard for long, as she quickly will be hardly weight bearing and very gimpy the next day. I'm hoping I can get her well enough for at least 2 trails walks (2-3ish miles) and 2 walks around the block (.5-1mile) a week. At the very least, if we could get 2 trail walks in and I could bring her to the barn with me 3-4 days a week (mostly casual walking/sniffing around the barnyard) I think she would be content. As much as I would love to get her out and exercised every day, I am acknowledging that she is a senior giant breed dog and it may not be possible.

I understand that Adequan is supposedly excellent at slowing the furthering of osteoarthritis, and I have read that it often alleviates symptoms of joint degeneration that are already present. I guess my question is, has anyone here used Adequan for an arthritic old dog? What kind of improvements, if any, did you see? Do you think it could potentially get a dog from being mildly lame just walking around the house to being able to walk/trot a few miles (mostly flat ground) with no or mild lameness afterwards? I asked my vet these questions, of course, but she was very "we will have to see how she responds". Which is true, of course, but I'd appreciate any firsthand experience.
 

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I used Adequan for Sor as a preventative. He never showed signs of serious arthritis and only really moved different when the bone cancer got bad. But I do remember him being more spry after the Adequan injection. I would not hesitate to use it again. I also did the IM injections myself (there are some sources that say SQ would work but I've always stuck with IM). However, it's important to know where to do it because if done incorrectly you can hit a nerve with the needle.
 

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Discussion Starter #3
I used Adequan for Sor as a preventative. He never showed signs of serious arthritis and only really moved different when the bone cancer got bad. But I do remember him being more spry after the Adequan injection. I would not hesitate to use it again. I also did the IM injections myself (there are some sources that say SQ would work but I've always stuck with IM). However, it's important to know where to do it because if done incorrectly you can hit a nerve with the needle.
Thanks for your input! Good to hear it seemed to make a difference for him. My vet is going to show me how to administer the shots IM so I don't have to bring her in every time, especially since she hates nothing more than the vet. I administer shots for my horses all the time so I'm pretty comfortable with it, but want to observe the vet do it once before I'm on my own since obviously the anatomy is quite different than what I'm used to.
 

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Discussion Starter #4
Just remembered I made this thread and figured I should update it for anyone who may come across it in the future.

In our case, Dasuquin proved to be much more beneficial for her than the Adequan. I did the initial loading of Adequan, but opted not to continue as I did not see any improvement from the Adequan and Dasuquin versus her on the Dasuquin alone.

I've spent the first half of this year working on building up her muscle again and she can now tolerate much more activity without her arthritis really flaring up. She is not 100% sound even with the Dasuquin - nor was she with Adequan, or with Deramaxx, nor a combo of all 3. At a walk I'd say she's about 80-90% sound (around the house she's close to 100%, but walking briskly for extended periods of time 80-90%). At a trot she goes down significantly and has a pretty evident limp, but it doesn't slow her down. I have taken her on short but strenuous hikes as well as mostly flat but longer (3-4 miles) walks/hikes, after which she is sore the next day, but with a double dose of Dasuquin she's good to go again within 2 days of a tougher hike. It's a balancing act between keeping her fit and active but not allowing her to push too hard, but it isn't too difficult. I've stopped walking her on pavement, so we only do off leash walks on dirt/grass now to try and alleviate pressure on her joints.

The vet and I have chatted about knee braces, but there's a lot of contradicting information out there about them, and to get a "proper" one that has a decent shot at actually working involves xrays and costly production. But it may be in our future.

For a 110lb 10 year old dog who was a pediatric spay and was significantly overweight the first 4-5 years of her life, I'll take it. Our club is doing a canine conditioning class in August which I may sign her up for, as it seems to resemble physical therapy but is more affordable.
 

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Thanks for the update! I'm glad you're figuring out what works and what doesn't. It's actually really impressive that you kept a dog so healthy and active with the cards stacked against her, so to speak. I hope you continue to see progress with Dasuquin and that you guys get to enjoy many more sunny days outside!
 

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Thanks for the update! I'm glad you're figuring out what works and what doesn't. It's actually really impressive that you kept a dog so healthy and active with the cards stacked against her, so to speak. I hope you continue to see progress with Dasuquin and that you guys get to enjoy many more sunny days outside!
Thank you! I hope so as well! I'm a firm believer that exercise is medicine - for the body and for the soul :)
 
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