If it's possible, I would recommend taking a few weeks of your vacation time when you bring the pup home. That way you can concentrate on getting the puppy settled in (and survive those first few sleepless nights with the crying). After that if you can make a stop home during the day or maybe hire a dog walker to come let the pup out you should be fine. I always feel guilty for leaving my dog home when I go to work all day, but I have yet to meet someone who is able to stay home 24 hours a day to entertain and care for their dog!