I'm heartbroken, I had to have my 4 1/2 month old puppy put to sleep due to a DHPP vaccine reaction that destroyed her bone marrow. After she received the vaccine (her second set) the first indication of problem was swelling and vomiting, the very next day I took her back to the vet and they gave her two more injections to counteract any allergic reaction. Next day, she still had a large swelling and refused to eat. This launched a two week period of hospitializations and emergency night runs to the 24 hour clinic, once with a 105.5 fever. All of the tests were fine until 5 days later, her cbc was normal but showed she was slightly anemic, she hadn't been eating and was on IV fluids during her hospitalizations. A week later and Pie was so lethargic, the vet did a bone marrow aspiration and discovered Pie was destroying/not making red or white blood cells. She started a transfusion and sent labs out, since it was Saturday the results wouldn't be back until Monday. The vet had ruled out everything but Leukemia which is very rare so we decided to treat for the auto immune reaction as it was the only thing it could be. The next day inspite of the transfusion her red count was down to 10 and although she hadn't fully regained consciousness from the anesthesia given for the bone marrow aspiration, she was beginning to moan. It was time to let her go.
The vet asked if it were okay to obtain additional bone marrow samples and a liver biopsy. I said whatever you need to keep another puppy from going thru this just do it. Thankfully she covered her bases with this. In the following week my vet has been in contact with the vaccine maker. Their vets are saying they have never seen such a severe reaction where the bone marrow is actually destroyed, immune mediated hemolytic anemia yes but destruction of the ability to make blood cells no. Since we've ruled out anything organic causing the problem the manufacturer is saying the only known substance to cause this is an overdose of a chemotherapy drug or a pharmaceutical grade poison. They have asked my vet to catalog lot numbers and inventory every vaccine she has on hand, want all records and samples. They are also offering to pay for all expenses not just from the vaccine reaction on but from the very beginning, even the puppy food I bought at the vet when I first brought her home.
This makes me suspicious as hell. I want to know how many other dogs have died from this? Pie was such a sweetheart, dumped with mom and three other nursing puppies at some awful rural kill shelter. Everybody had found homes except for her, she was going to be put down. When I brought her home she was 3 months old, had known no human contact other than someone filling the food bowl, had never walked on anything other than the concrete kennel. She asked for nothing, she deserved so much better than this. She was my companion and went to work with me every day, I can't believe she is gone. I can't tell you how many times I said to the vet... she was fine until she got the vaccine, they won't listen. Well now the vet is a believer and sadly it took my puppy's life to prove it.
How would I go about finding out if others have lost their dogs to this same "mistake"? I know I was only trying to protect her from deadly diseases but I feel like I betrayed her. My vet summed it up by saying how terrible she felt and that her first vow was to "do no harm".